VIP excess from tumours: secretory diarrhoea in two case reports (2026)
A 2026 case report describes two VIP-secreting neuroendocrine tumours that caused severe secretory diarrhoea and electrolyte abnormalities; one patient improved after adrenalectomy, the other had persistent symptoms despite debulking and somatostatin analogues.
Context: Two patients; endogenous VIP hypersecretion.
Limitations: Case report of endogenous VIP excess; says nothing about administered VIP or any dose.