RESEARCH ATLASRESEARCH > HYPE
PUBLIC RESEARCH EDITION
Mitochondrial / energy

AICAR

Mechanism not verified by source image · Small molecule

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Records (1)

H

Human clinical / research

Human clinical / research

Acadesine in RED-CABG

Administration reported for this specific study or labeled indication.

Context: Adults undergoing coronary artery bypass grafting

Human study regimen: Amount: 0.1 mg/kg/min IV; 5 µg/mL in cardioplegia; Route: Intravenous infusion plus cardioplegia; Frequency: Perioperative; Duration: Approximately 7 hours for the IV infusion; Species: Human; Population: Adults undergoing coronary artery bypass grafting

Limitations: The randomized trial did not demonstrate a significant benefit on its primary composite endpoint.

Route: Intravenous infusion plus cardioplegia

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Glutathione2 labeled records →L-carnitine1 labeled records →MOTS-c17 labeled records →NAD+1 labeled records →SS-31 / Elamipretide10 labeled records →Urolithin A4 labeled records →
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Educational research summary. Study amounts are research context, not a dose recommendation. Not medical advice.